For example, chronic stress can lead to decreased testosterone levels, while stress management techniques, such as meditation and yoga, can help mitigate this effect. On the other hand, a sedentary lifestyle, poor sleep, and exposure to endocrine-disrupting chemicals can negatively impact testosterone levels. For instance, a diet rich in essential nutrients, such as zinc, magnesium, and vitamin D, can support healthy testosterone production. Environmental and lifestyle factors can significantly influence testosterone levels, with factors such as diet, exercise, and sleep playing a crucial role. Understanding the connection between testosterone and acne is crucial for anyone looking to reclaim their skin’s clarity and confidence. Learn more about the potential signs that low testosterone levels may be a result of high amounts of stress. Some treatments may work better for acne prone skin than others. Medications for acne caused by testosterone may need to be taken for longer than other kinds of hormonal acne. In the beginning stages of acne treatment, it’s not uncommon to feel like your acne worsens before it gets better. Testosterone may cause the skin to overproduce oil which leads to hormonal acne. Acne from testosterone therapy tends to be more persistent than occasional acne. Insurers typically require symptoms plus two low morning testosterone results and periodic labs. When you confirm the diagnosis, match the formulation to your life, and monitor smartly, you can expect meaningful gains in energy, sexual health, and body composition, without trading away safety. Low testosterone therapy in 2026 is both more precise and more flexible. Most clinicians aim for mid‑normal total testosterone (often ~400–700 ng/dL), individualized to symptom control and side effects. Testosterone therapy suppresses sperm production, sometimes to zero, within months. If you’re trying to conceive, avoid standard testosterone, it suppresses sperm production. Long-acting testosterone undecanoate (administered in clinic) offers stable levels with less frequent dosing but requires monitoring for rare reactions. Another study published in the Pan African Medical Journal in 2022 compared hormone levels in 70 females with acne and 70 females without acne. The next study, published in the New England Journal of Medicine in 1996, also looked at the effects of giving testosterone to healthy men. The researchers found that half of the men in the study developed acne as a side effect of the testosterone, and that the acne cleared up after the testosterone treatment ended. At the beginning of the study, the average amount of total testosterone in their blood was 16.4nmol/l, which is approximately in the middle of the normal range for healthy men. A third study, published in the Journal of Clinical Endocrinology and Metabolism in 1994, set out to investigate the effects of giving healthy men high doses of testosterone. The researchers noted that the castrated men produced less skin oil than healthy men and did not have acne. With a dermatologist’s help, you can successfully treat acne and keep your dose of testosterone where it is. I’ve seen patients stop their gender-affirming therapy entirely when acne became more than they could tolerate. A dermatologist is a medical doctor who specializes in treating the skin, hair, and nails. They can work with you to diagnose the cause of your acne and determine the best treatment. Your production of testosterone tends to start dropping after the age of 30. However, hormonal acne can persist throughout adulthood. TRT has certain risks and benefits, so your healthcare provider will carefully evaluate if it’s safe and right for you. "In cases where high testosterone levels contribute to acne, it’s essential to evaluate hormone balance. By adopting a multifaceted approach that includes skincare, dietary changes, and professional guidance, individuals can effectively manage acne linked to testosterone levels. In addition to medical treatments, lifestyle changes and skincare routines can play a pivotal role in reducing acne linked to testosterone. A licensed healthcare provider can order lab work for you to determine your eligibility for treatment if clinically appropriate. Be sure to let a healthcare provider know if you are taking any vitamins or supplements before starting a medication for your acne. Elevated testosterone levels may contribute to acne by increasing your body’s production of a substance called sebum.